Pathology EMQ template.

Name: Vinesh Nalin Patel

Candidate number: 

Theme: Therapeutic Drug Monitoring

 

OPTION LIST

 

A	Phenytoin	I	Chloramphenicol
B	Gentamicin	J	Crack cocaine
C	Lithium	K	Clozapine
D	Theophylline	L	Azathioprine
E	Paracetamol	M	Methotrexate
F	Erythromycin	N	Mycophenolate mofetil
G	Heparin - unfractionated	O	Fluconazole
H	Ritonavir	P	Digoxin

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. Monitoring levels of this drug to keep it in a set range is a way of minimising risk of grey baby syndrome

 

 

2. An immunosuppressive drug which could cause toxicity in patients with low albumin levels (even with doses within the normally therapeutic range), just as is the case for phenytoin

 

 

3. Can cause ototoxicity and nephrotoxicity

 

 

4. This drug is potentiated by hypothyroidism and hypokalaemia. Monitor it at least 6 hours post-dose, to prevent e.g. arrhythmia

 

 

5. This drug is a CYP P450 enzyme substrate, inducer & inhibitor

 

 

ANSWERS

1. I

2. N

3. B

4. P

5. H